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Interleukin-1 induces interleukin-1α and interleukin-1β gene expression in synovial fibroblasts and peripheral blood monocytes

✍ Scribed by Barbara J. Dalton; Janice R. Connor; William J. Johnson

Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
896 KB
Volume
32
Category
Article
ISSN
0004-3591

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## Abstract Osteopontin is a multifunctional matricellular protein identified as one of the most upregulated genes in pulmonary fibrosis. Experimental animal models have identified early pro‐fibrotic cytokines as essential to the pathogenesis of inflammation‐induced pulmonary fibrosis. However, the