Interleukin-1 induces a nuclear form of transcription factor NFκB in human lung epithelial cells
✍ Scribed by K. P. Ray; N. Kennard
- Publisher
- SP Birkhäuser Verlag Basel
- Year
- 1993
- Tongue
- English
- Weight
- 160 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1420-908X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract IL‐1β is an important mediator in the pathogenesis of type 1 diabetes both in vivo and in vitro and it has been shown to induce islet β‐cell apoptosis. Most of the IL‐1β effects seem to be mediated by NF‐κB transcription factor activation, but its role in the induction of islet β‐cell a
## Abstract Deoxycholic acid (DCA) has been implicated in colorectal carcinogenesis in humans with effects on proliferation and apoptosis, mediated at least in part by activation of transcription factors nuclear factor kappa B (NF‐κB), activator protein 1 (AP‐1) and protein kinase C (PKC) enzymes.
## Abstract The new disaccharide anthracycline MEN 10755 induces activation of both NF‐κB and p53 transcription factors in A2780 cells. Nevertheless, pharmacologic inhibition of NF‐κB activation does not modify the sensitivity of A2780 cells to MEN 10755 treatment. To better characterize the role o
## Abstract CXCL8 is a CXC chemokine that recruits leukocytes to sites of inflammation. Expression of CXCL8 in the CNS has been demonstrated in neuroinflammatory diseases, including human immunodeficiency virus (HIV‐1) encephalitis, but the mechanism of secretion of this chemokine is not fully unde
## Abstract Interleukin‐1β (IL‐1β) has been shown to induce the expression of intercellular adhesion molecule‐1 (ICAM‐1) on airway epithelial cells and contributes to inflammatory responses. However, the mechanisms regulating ICAM‐1 expression by IL‐1β in human A549 cells was not completely underst