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Interleukin-1 (IL-1) Receptor Type I Mediates Anorexia but not Adipsia Induced by Centrally Administered IL-1β

✍ Scribed by Gayatri Sonti; Mark C Flynn; Carlos R Plata-Salamán

Book ID
117198823
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
119 KB
Volume
62
Category
Article
ISSN
0031-9384

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## Abstract Endothelial cells (EC) are very responsive to the proinflammatory cytokine inter‐leukin‐1 (IL‐1). EC are induced by IL‐1 to secrete chemotactic factors and to increase expression of cell surface adhesion molecules leading to increased leukocyte adhesion. Activated EC turther contribute