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Interleukin 1 and T-cell activation

✍ Scribed by Antonio Campos-Neto; Philip P. Stashenko


Book ID
103583151
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
153 KB
Volume
9
Category
Article
ISSN
0167-5699

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Clonal deletion represents an important mechanism for the establishment of tolerance, by the elimination of autoreactive T cells. Deletion is accomplished by programmed cell death, termed apoptosis, induced by mobilization of the T cell receptor (TCR) on both thymocytes and mature T cells. The mecha