A review of the clinical studies in which interferons have been involved has shown that they may have a role in the treatment of multiple myeloma. Twelve studies, each of which involved at least 10 evaluable cases (352 in total) with various dose schedules involving leukocyte, lymphoblastoid and rec
Interferons in the treatment of multiple myeloma
β Scribed by M. Robert Cooper; Charles E. Welander
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 631 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. Interferon (IFN) has demonstrated activity in the treatment of patients with multiple myeloma. A previous Eastern Cooperative Oncology Group (ECOG) study suggested that the rates of complete response (CR) and survival were increased with a regimen that alternated IFN with chemothera
The present pilot study was designed to analyse the efficacy and toxicity of the association of interferon (IFN) and dexamethasone (Dx) in 32 resistant and relapsed myeloma patients. Among the evaluable cases, 15 (68 per cent) responded to treatment (32 per cent achieved an objective respons4R-and 3