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Interferons impair early transgene expression by adenovirus-mediated gene transfer in muscle cells

✍ Scribed by G. Acsadi; David O’Hagan; Hanns Lochmüller; Stephen Prescott; Nancy Larochelle; Josephine Nalbantoglu; Agnes Jani; George Karpati


Book ID
105797408
Publisher
Springer
Year
1998
Tongue
English
Weight
705 KB
Volume
76
Category
Article
ISSN
0946-2716

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## Abstract ## Background It has previously been shown that oxidants reduce the efficiency of adenoviral transduction in human umbilical vein endothelial cells (HUVECs). In this study, the effect of the antioxidant __N__‐acetylcysteine (NAC) in adenovirus‐mediated gene transfer has been investigat