Negative modulation of α1(I) procollagen
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Weihua Yuan; Tatyana Yufit; Liye Li; Yasuji Mori; Shu-Jen Chen; John Varga
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Article
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1999
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John Wiley and Sons
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English
⚖ 331 KB
👁 1 views
Interferon-␥ (IFN-␥), a multifunctional cytokine produced by activated Th1 lymphocytes, exerts potent effects on the extracellular matrix by regulating fibroblast function. In this study, we examined the modulation of ␣1(I) procollagen gene (COL1A1) expression by recombinant IFN-␥. The results showe