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Interferon-γ induces 2, 3-dioxygenase expression in human peripheral blood eosinophils: Role in eosinophil survival?

✍ Scribed by Ghahary, A.G.; Odemuyiwa, S.O.; Lee, J.; Ghahary, A.; Moqbel, R.; Ghahary, A.G.

Book ID: 119491407
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 117 KB
Volume: 111
Category: Article
ISSN: 1097-6825
DOI: 10.1016/s0091-6749(03)80342-1

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## Abstract Indoleamine 2,3‐dioxygenase (IDO), a tryptophan‐catabolizing enzyme, is an intracellular enzyme possessing various immunosuppressive properties. Here, we report the possible use of this enzyme to suppress proliferation of immune cells cocultured with IDO‐expressing fibroblasts of an all