Interferon type I gene expression in chronic hepatitis C
โ Scribed by Mihm, Sabine; Frese, Michael; Meier, Volker; Wietzke-Braun, Perdita; Scharf, Jens-Gerd; Bartenschlager, Ralf; Ramadori, Giuliano
- Book ID
- 109885778
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 393 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0023-6837
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Hepatitis C virus (HCV) infection is a major cause of chronic liver disease. Treatment with interferon-alpha 2 (IFN-a 2 ) can induce viral clearance and marked biochemical and histological improvement. IFN-a 2 treatment has been shown to stimulate the expression of type I IFN regulated genes in peri
Tumor necrosis factor a (TNF-a) is a cytokine with infectious agents and has been shown to exert direct pleiotropic properties that is induced in a variety of antiviral effects. [3][4][5] Although low levels of TNF-a can pathological situations including viral infections. In this contribute to cell
Interferon (IFN) receptor mRNA expression patterns in the liver have been shown to correlate with the effectiveness of IFN therapy in patients with hepatitis C virus (HCV) infection. However, it is not clear to what extent this factor contributes to the short (primary)-and long (sustained)term resul