Interferon therapy for aged patients with chronic hepatitis C: improved survival in patients exhibiting a biochemical response
β Scribed by Yasuharu Imai; Akinori Kasahara; Hideo Tanaka; Takeshi Okanoue; Naoki Hiramatsu; Hirohito Tsubouchi; Kentaro Yoshioka; Sumio Kawata; Eiji Tanaka; Keisuke Hino; Katsuhiro Hayashi; Shinji Tamura; Yoshito Itoh; Yutaka Sasaki; Kendo Kiyosawa; Shinichi Kakumu; Kiwamu Okita; Norio Hayashi
- Publisher
- Springer Japan
- Year
- 2004
- Tongue
- English
- Weight
- 208 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0944-1174
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## Abstract The aim of this study was to elucidate the reduction of hepatocarcinogenesis by prolonged interferon (IFN) monotherapy in aged chronic hepatitis C patients. Inclusion criteria were biopsyβproven chronic hepatitis or liver cirrhosis, 60 years and over, elevated serum aminotransferase and
Recent studies performed in Japan have suggested that hepatitis C virus (HCV) genome heterogeneity might be taken as a predictive virological parameter of response to interferon alfa (IFN-alpha) treatment. However, there is presently no information on the impact of this virological parameter in pati