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Interferon reduces somatic mutation of mitochondrial DNA in liver tissues from chronic viral hepatitis patients

✍ Scribed by M. Nishikawa; S. Nishiguchi; K. Kioka; A. Tamori; M. Inoue


Book ID
108885786
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
97 KB
Volume
12
Category
Article
ISSN
1352-0504

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Hepatitis C virus (HCV) infection induces the endogenous interferon (IFN) system in the liver in some but not all patients with chronic hepatitis C (CHC). Patients with a pre-activated IFN system are less likely to respond to the current standard therapy with pegylated IFN-alpha. Mitochondrial antiv