The interaction of human recombinant interferon (rlFN) a2 with its receptor on lymphoblastoid cells was studied using competitive displacement binding. The data were analysed with the LIGAND program, which tests their fit to one-site or multiple binding site models. The binding at 4 O and 37OC fits
✦ LIBER ✦
Interferon receptor interaction : Internalization of interferon α2 and modulation of its receptor on human cells
✍ Scribed by Fazlul H. SARKAR; Sohan L. GUPTA
- Book ID
- 115122420
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 972 KB
- Volume
- 140
- Category
- Article
- ISSN
- 1432-1327
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## Modulation of interferon-y receptor during human T lymphocyte alloactivation* Previous work has shown that neutralization of physiologically secreted interferon(IFN)-y or blockade of its receptor during T lymphocyte activation inhibits both proliferation and cytotoxicT lymphocyte generation, su