Interferon pretreatment enhances the sensitivity of Vero cells to Clostridium perfringens type A enterotoxin
β Scribed by Bruce A. McClane; Andrew P. Wnek; Patricia Whitaker-Dowling
- Book ID
- 118245350
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 855 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0882-4010
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π SIMILAR VOLUMES
## Abstract Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to __Clostridium perfringens__ enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detache
The mechanism by which Clostridium perfringens enterotoxin (CPE) simultaneously inhibits RNA, DNA, and protein synthesis i s unknown. In the current study the possible involvement of small molecule permeability alterations in CPE-induced inhibition of macromolecular synthesis was examined. Vero cell