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Interferon induction by cell-cell interaction of HIV-infected monocytes/macrophages with lymphocytes

✍ Scribed by Rokos, K; Pauli, G


Book ID
122534105
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
518 KB
Volume
142
Category
Article
ISSN
0923-2516

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We analyse mathematical models comparing the in vivo dynamics of macrophage-and T cell infection by HIV. Experiments suggest that HIV can only replicate in activated T cells whereas cell activation may not be required for successful replication in macrophages. These assumptions lead to fundamentally