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Interferon-Induced Guanylate Binding Protein-1 (GBP-1) Mediates an Antiviral Effect against Vesicular Stomatitis Virus and Encephalomyocarditis Virus

✍ Scribed by Sylvia L. Anderson; Jill M. Carton; Jing Lou; Lily Xing; Berish Y. Rubin

Book ID: 112272479
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 149 KB
Volume: 256
Category: Article
ISSN: 0042-6822
DOI: 10.1006/viro.1999.9614

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Interferons (IFNs) and the interferon-stimulated genes (ISGs) play a central role in antiviral responses against hepatitis C virus (HCV) infection. We have reported previously that ISGs, including guanylate binding protein 1 (GBP-1), interferon alpha inducible protein (IFI)-6-16, and IFI-27, inhibit