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Interferon-gamma induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1)

✍ Scribed by Peiyuan Li; Qiang Du; Zongxian Cao; Zhong Guo; John Evankovich; Wei Yan; Ying Chang; Lifang Shao; Donna Beer Stolz; Allan Tsung; David A. Geller

Book ID: 116335771
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 963 KB
Volume: 314
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2011.09.031

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## Abstract Ascochlorin, a non‐toxic prenylphenol compound derived from the fungus __Ascochyta viciae__, has been shown recently to have anti‐cancer effects on various human cancer cells. However, the precise molecular mechanism of this anti‐cancer activity remains to be elucidated. Here, we invest