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Interferon-alpha induces circulating tumor necrosis factor receptor p55 in humans

✍ Scribed by Herbert Tilg; Wolfgang Vogel; Charles A. Dinarello

Book ID
116172566
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
151 KB
Volume
6
Category
Article
ISSN
1043-4666

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The present study examined differentiation-inducing activity by various tumor-necrosis-factor(TNF) mutants against the human leukemic cell lines HL-60 and U-937. Mutant TNF 471, from which 7 N-terminal amino acids of native TNF were deleted and Pro 8 , Ser 9 and Asp 10 were replaced by Arg, Lys and