Trisomy 21 human fibroblasts are more sensitive to human interferon-alpha (IFN-alpha) than are diploid controls, consistent with the location of the gene (IFRC) which codes for the IFN-alpha receptor on chromosome 21. When compared in the antiviral assay, the difference in sensitivity is five- to te
Interferon action in human fibroblasts: Induction of 2′, 5′-oligoadenylate synthetase in the absence of detectable protein kinase activity
✍ Scribed by Sandra L. Holmes; S. L. Gupta
- Publisher
- Springer Vienna
- Year
- 1982
- Tongue
- English
- Weight
- 516 KB
- Volume
- 72
- Category
- Article
- ISSN
- 1432-8798
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