Defective DNA repair capacity as measured by enumerating chromatid aberrations induced in G 2 phase by X-irradiation may explain increased risk of breast cancer among relatives of patients. In the present study, chromatid damage was determined in peripheral blood lymphocytes (PBL) following in vitro
Interest in genetic testing among first-degree relatives of breast cancer patients
β Scribed by Lerman, Caryn ;Seay, Janet ;Balshem, Andrew ;Audrain, Janet
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 900 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The increased risk of nonocular cancer seen consistently in studies of survivors of retinoblastoma may be caused in part by the presence of a retinoblastoma gene that also predisposes to other cancers. It has been claimed that this gene also increases the risk for cancer among unaffected relatives o
Previous research has suggested that demand for genetic testing for breast cancer susceptibility may be quite high, even among those at relatively low risk of carrying a mutation. This study examined the extent to which a group of female HMO enrollees were aware of the discovery of the BRCA1 gene an
The present investigation sought to determine (1) the impact of a single session stress management/coping intervention (problem-solving training; PST) versus a general health counseling (GHC) control condition on breast self-examination (BSE) adherence among relatives of newly diagnosed breast cance