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Interdomain interaction through helices A and B of DnaK peptide binding domain

✍ Scribed by Fernando Moro; Vanesa Fernández; Arturo Muga


Book ID
117104975
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
173 KB
Volume
533
Category
Article
ISSN
0014-5793

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## Abstract Grb7 is a member of the Grb7 family of proteins, which also includes Grb10 and Grb14. All three proteins have been found to be overexpressed in certain cancers and cancer cell lines. In particular, Grb7 (along with the receptor tyrosine kinase erbB2) is overexpressed in 20–30% of breast