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Interdependence of Gene Expression for Early Steps of Cephalosporin Synthesis in Streptomyces clavuligerus

✍ Scribed by A. L. DEMAIN; J. M. PIRET; H. YU; J.-J. COQUE; P. LIRAS; J. F. MARTIN

Book ID
119871101
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
306 KB
Volume
721
Category
Article
ISSN
0890-6564

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The cefD and cefE genes of Nocardia lactamdurans, which encode isopenicillin N epimerase and deacetoxycephalosporin C synthase respectively, have been located 0.63 kb upstream from the lysine-6-amino-transferase (lat) gene. cefD contains an open reading frame (ORF) of 1197 nucleotides (nt) encoding