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Intercompany Study to Evaluate the Robustness of Capillary Isoelectric Focusing Technology for the Analysis of Monoclonal Antibodies

โœ Scribed by Oscar Salas-Solano; Kunnel Babu; SungAe Suhr Park; Xinfeng Zhang; Li Zhang; Zoran Sosic; Boris Boumajny; Ming Zeng; Kuang-Chuan Cheng; Angelia Reed-Bogan; Stacey Cummins-Bitz; David A. Michels; Monica Parker; Paulina Bonasia; Mingfang Hong; Steven Cook; Margaret Ruesch; David Lamb; Dora Bolyan; Steffen Kiessig; Darren Allender; Brian Nunnally

Book ID
106317153
Publisher
Springer
Year
2011
Tongue
English
Weight
280 KB
Volume
73
Category
Article
ISSN
0009-5893

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๐Ÿ“œ SIMILAR VOLUMES

A high-resolution capillary isoelectric
A high-resolution capillary isoelectric focusing method for the determination of therapeutic recombinant monoclonal antibody
โœ Jun Lin; Qingqiao Tan; Shaoxiong Wang ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 246 KB

## Abstract Capillary isoelectric focusing (CIEF) is a common choice for separation and analysis of the charge variants and impurities of therapeutic proteins. In this study, we developed a sensitive CIEF analysis method for determining the charge heterogeneity of therapeutic monoclonal antibody (m