Interchangeability of mutagens during fractional exposure to unequal concentrations of alkylating agents

Increased cotransformation of distant ma

Increased cotransformation of distant markers and altered patterns of DNA-cell interactions following the exposure of transforming DNA to two carcinogenic and mutagenic alkylating agents, diethyl and dimethyl sulfate

✍ Z. O. Kubinski; H. Kubinski 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 685 KB

Transforming DNA exposed to either diethyl sulfate (diES) or dimethyl sulfate (diMS) is inactivated. The rate of inactivation depends on the marker tested and on the chemical used: diMS is more active than diES. Cotransformation of linked markers is similarly depressed. In contrast, there is a trans