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Intercellular adhesion molecule 1 underlies the functional heterogeneity of synovial cells in patients with rheumatoid arthritis: Involvement of cell cycle machinery

✍ Scribed by Yoshiya Tanaka; Masashi Nomi; Koichi Fujii; Stefan Hübscher; Akihiko Maruo; Shigeru Matsumoto; Yuichiro Awazu; Kazuyoshi Saito; Sumiya Eto; Yasuhiro Minami

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
879 KB
Volume
43
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To investigate the roles of MAPKs and NF‐κB in tumor necrosis factor α (TNFα)–induced expression of vascular cell adhesion molecule 1 (VCAM‐1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f