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Interactions of the M2δ Segment of the Acetylcholine Receptor with Lipid Bilayers: A Continuum-Solvent Model Study

✍ Scribed by Kessel, Amit; Haliloglu, Turkan; Ben-Tal, Nir

Book ID
118515531
Publisher
Biophysical Society
Year
2003
Tongue
English
Weight
341 KB
Volume
85
Category
Article
ISSN
0006-3495

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## Abstract The transmembrane domain of the nicotinic acetylcholine receptor (nAChR) plays a role in the regulation of the activity of this important ligand‐gated ion channel. The lipid composition of the host membrane affects conformational equilibria of the nAChR and several classes of inhibitors