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Interactions of Substrate and Product with Cytochrome P450: P4502B4versus P450cam

โœ Scribed by Shakunthala Narasimhulu; Lisa M. Havran; Paul H. Axelsen; Jeffery D. Winkler


Book ID
115567111
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
226 KB
Volume
353
Category
Article
ISSN
0003-9861

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We present an analysis of several molecular dynamics trajectories of substrate-bound cytochrome P450cam. Trajectories were calculated for the native substrate, camphor, as well as for the alternative substrates, norcamphor and thiocamphor. The system modeled consisted of the crystallographically res