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Interactions of isoniazid with membrane models: Implications for drug mechanism of action

✍ Scribed by Pinheiro, Marina; Silva, Ana Sofia; Pisco, Sílvia; Reis, Salette

Book ID: 125821772
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 848 KB
Volume: 183
Category: Article
ISSN: 0009-3084
DOI: 10.1016/j.chemphyslip.2014.07.002

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In the absence of scheduled shocks cyclazocine (2.5 mg/kg) severely depressed avoidance responding. No behavioural excitation was observed. Behavioural excitation is observed after cyclazocine (2.5 mg/kg) injection, in the presence of scheduled shocks. The excitatory phase associated with the drug i