Molecular Dynamics Simulation of HIV-1 I
β
Jianping Hu; Cunxin Wang
π
Article
π
2010
π
John Wiley and Sons
π
English
β 403 KB
The biological function of HIV-1 integrase (IN) is to integrate viral DNA into the host cell chromosome, and the specific binding of IN with viral DNA is a precondition for IN to function correctly. Beforehand, the binding mode of IN dimer (IN 2 ) with the 27 bp segment of viral DNA before 3' proces