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Interactions of Endocrine-active environmental chemicals with the nuclear receptor PXR

✍ Scribed by Hurst, Christopher H; Waxman, David J

Book ID: 118227544
Publisher: Taylor and Francis Group
Year: 2005
Tongue: English
Weight: 215 KB
Volume: 87
Category: Article
ISSN: 0277-2248
DOI: 10.1080/02772240400026781

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## Abstract The human pregnane X receptor (PXR) is a member of the nuclear receptor superfamily of ligand‐regulated transcription factors. PXR responds to a structurally diverse variety of endogenous and xenobiotic compounds, and coordinates the expression of genes central to the metabolism and exc