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Interactions of cyclic hexapeptide cyclo(Pro-Sar-Sar)2 with small molecules

✍ Scribed by S. Kimura; Y. Imanishi


Book ID
119069705
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
439 KB
Volume
3
Category
Article
ISSN
0141-8130

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Crystal structure and conformation of a
✍ Katsuhiko Ueno; Toshimi Shimizu πŸ“‚ Article πŸ“… 1983 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 419 KB πŸ‘ 1 views

## Abstract The crystal structure and conformation of the synthetic cyclic tetrapeptide, __cyclo__(L‐Pro‐Sar)~2~, was determined by x‐ray analysis. The peptide crystallizes in the orthorhombic space group __P__2~1~2~1~2~1~ with cell parameters __a__ = 9.277(1), __b__ = 12.884(1), and __c__ = 15.581

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The interaction between cyclic peptides [cyclo-(Sara), cyclo-(Pro-Sar-Gly)r, cyclo-(Sar-Sar), and cyclo-(Sar-Gly)] with benzene has been investigated by nmr spectroscopy. The experiment with cyclo-(Sarr) showed that benzene int,eracted preferentially with the frans peptide bond in a similar manner t