Interactions of cyclic hexapeptide cyclo(Pro-Sar-Sar)2 with small molecules
β Scribed by S. Kimura; Y. Imanishi
- Book ID
- 119069705
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 439 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0141-8130
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## Abstract The crystal structure and conformation of the synthetic cyclic tetrapeptide, __cyclo__(LβProβSar)~2~, was determined by xβray analysis. The peptide crystallizes in the orthorhombic space group __P__2~1~2~1~2~1~ with cell parameters __a__ = 9.277(1), __b__ = 12.884(1), and __c__ = 15.581
The interaction between cyclic peptides [cyclo-(Sara), cyclo-(Pro-Sar-Gly)r, cyclo-(Sar-Sar), and cyclo-(Sar-Gly)] with benzene has been investigated by nmr spectroscopy. The experiment with cyclo-(Sarr) showed that benzene int,eracted preferentially with the frans peptide bond in a similar manner t