✦ LIBER ✦

Interactions of Conformationally Biased North and South 2‘-Fluoro-2‘,3‘-dideoxynucleoside 5‘-Triphosphates with the Active Site of HIV-1 Reverse Transcriptase

✍ Scribed by Mu, Lan; Sarafianos, Stefan G.; Nicklaus, Marc C.; Russ, Pamela; Siddiqui, Maqbool A.; Ford, Harry; Mitsuya, Hiroaki; Le, Richard; Kodama, Eiichi; Meier, Chris; Knispel, Tina; Anderson, Lynne; Barchi, Joseph J.; Marquez, Victor E.

Book ID: 126422836
Publisher: American Chemical Society
Year: 2000
Tongue: English
Weight: 723 KB
Volume: 39
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi001090n

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 2‘,3‘-Dideoxynucleoside 5‘-

Synthesis of 2‘,3‘-Dideoxynucleoside 5‘-α- P -Borano-β,γ-(difluoromethylene)triphosphates and Their Inhibition of HIV-1 Reverse Transcriptase

✍ Boyle, Nicholas A.; Rajwanshi, Vivek K.; Prhavc, Marija; Wang, Guangyi; Fagan, P 📂 Article 📅 2005 🏛 American Chemical Society 🌐 English ⚖ 128 KB

Syntheses of Pyrrolo[2,3-d]pyrimidine 2′

Syntheses of Pyrrolo[2,3-d]pyrimidine 2′,3′-Dideoxyribonucleosides Related to 2′,3′-Dideoxyadenosine and 2′,3′-Dideoxyguanosine and Inhibitory Activity of 5′-Triphosphates on HIV-1 Reverse Transcriptase

✍ Frank Seela; Heinz-Peter Muth; Angelika Röling 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 German ⚖ 720 KB

## ~~~~~ ~ ~ ~ The synthesis of 4-chloropyrrolo[2,3-d]pyrimidine and 2-amino-4-chloropyrrolo[2,3-d]pyrimidine a -D-and ~-~-2',3'-dideoxyribonucleosides 6a, b and 7a, b is described (Scheme 1). Glycosylation of the pyrrolo[2,3-d]pyrimidinyl anions of la, b with in situ prepared 2,3-dideoxy-a /B-D-g

Synthesis and Biological Evaluation of 2

Synthesis and Biological Evaluation of 2‘,3‘-Didehydro-2‘,3‘-dideoxy-5- fluorocytidine (D4FC) Analogues: Discovery of Carbocyclic Nucleoside Triphosphates with Potent Inhibitory Activity against HIV-1 Reverse Transcriptase 1

✍ Shi, Junxing; McAtee, J. Jeffrey; Schlueter Wirtz, Susan; Tharnish, Phillip; Juo 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 128 KB

Thiated derivatives of 2′,3′-dideoxy-3′-

Thiated derivatives of 2′,3′-dideoxy-3′-fluorothymidine: Synthesis, in vitro anti-HIV-1 activity and interaction with recombinant drug resistant HIV-1 reverse transcriptase forms

✍ Agnieszka Miazga; François Hamy; Séverine Louvel; Thomas Klimkait; Zofia Pietrus 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 296 KB

Newly Synthesized l -Enantiomers of 3'-F

Newly Synthesized l -Enantiomers of 3'-Fluoro-Modified β-2'-Deoxyribonucleoside 5'-Triphosphates Inhibit Hepatitis B DNA Polymerases But Not the Five Cellular DNA Polymerases α, β, γ, δ, and ε Nor HIV-1 Reverse Transcriptase

✍ von Janta-Lipinski, Martin; Costisella, Burkhardt; Ochs, Hansueli; Hübscher, Ulr 📂 Article 📅 1998 🏛 American Chemical Society 🌐 English ⚖ 101 KB

ChemInform Abstract: Newly Synthesized L

ChemInform Abstract: Newly Synthesized L-Enantiomers of 3′-Fluoro-Modified β-2′-Deoxyribonucleoside 5′-Triphosphates Inhibit Hepatitis B DNA Polymerases But Not the Five Cellular DNA Polymerases α, β, γ, δ, and ε Nor HIV-1 Reverse Transcriptase.

✍ M. VON JANTA-LIPINSKI; B. COSTISELLA; H. OCHS; U. HUEBSCHER; P. HAFKEMEYER; E. M 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 41 KB 👁 1 views