Interaction médicamenteuse entre des ant
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E. Gaïes; I. Salouage; R. Sahnoun; S. Trabelsi; N. Jebabli; M. Lakhal; A. Klouz
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Article
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2011
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Masson Editeur
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French
⚖ 157 KB
Tacrolimus, an immunosuppressor indicated in solid organ transplantation, has a large inter- and intra-individual variability, a narrow therapeutic index and numerous drug interactions. It is metabolized in the enterocytes and the liver by CYP3A4. Association to enzymatic inhibitors like azole antif