Synovitis in rheumatoid arthritis is characterized by infiltration of the synovium by T and B lymphocytes and monocytes, as well as by the proliferation of synovial lining cells, fibroblasts, and endothelial cells. To study synovial cell-T cell interactions in vitro, we established cultures of fibro
โฆ LIBER โฆ
Interactions between T cells and synovial fibroblasts
โ Scribed by Y. Yamamura; E. Shelden; D. A. Fox
- Book ID
- 106292485
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 269 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1439-7595
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## Objective: To determine the impact of type ii collagen (cii)-reactive t cells on the production of chemokines in the joints of patients with rheumatoid arthritis (ra). ## Methods: T cell proliferative responses to bovine cii were assayed in synovial fluid (sf) mononuclear cells and peripheral