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Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

✍ Scribed by Carla Ferrada; Sergi Ferré; Vicent Casadó; Antonio Cortés; Zuzana Justinova; Chanel Barnes; Enric I. Canela; Steven R. Goldberg; Rob Leurs; Carme Lluis; Rafael Franco

Book ID
116785006
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
562 KB
Volume
55
Category
Article
ISSN
0028-3908

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am