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Interaction of β-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter

✍ Scribed by Lorena Pochini; Michele Galluccio; Domenica Scumaci; Nicola Giangregorio; Annamaria Tonazzi; Ferdinando Palmieri; Cesare Indiveri

Book ID
113517648
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
600 KB
Volume
173
Category
Article
ISSN
0009-2797

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Interaction of mildronate with the mitoc
Interaction of mildronate with the mitochondrial carnitine/acylcarnitine transport protein
✍ Francesca Oppedisano; Delia Fanello; Menotti Calvani; Cesare Indiveri 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 201 KB

## Abstract The interaction of mildronate [3‐(2,2,2‐trimethylhydrazine) propionate] with the purified mitochondrial carnitine/acylcarnitine transporter reconstituted in liposomes has been studied. Mildronate, externally added to the proteoliposomes, strongly inhibited the carnitine/carnitine antipo