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Interaction of Urea with Pluronic Block Copolymers by 1 H NMR Spectroscopy

✍ Scribed by Ma, Jun-he; Guo, Chen; Tang, Ya-lin; Chen, Lin; Bahadur, P.; Liu, Hui-zhou

Book ID
127313262
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
166 KB
Volume
111
Category
Article
ISSN
0022-3654

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The objective was to examine the influence of Pluronic block-copolymers on the interaction between the drug efflux transporter, P-glycoprotein and HIV-1 protease inhibitors (PIs). The ATPase assay determined the effect of various Pluronics on PI-stimulated P-gp ATPase activity. Cellular accumulation