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Interaction of Uranyl Ions with Daunorubicin and Adriamycin

✍ Scribed by Athanasios Papakyriakou; Angeliki Anagnostopoulou; Arlette Garnier-Suillerot; Nikos Katsaros

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
416 KB
Volume
2002
Category
Article
ISSN
1434-1948

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✍ C. Rolland Chen; Mary Tan Fon; Alan N. Fujiwara; David W. Henry; Morris A. Leaff 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 275 KB

## Abstract Reaction of adriamycinone with excess ^14^CH~3~Mgl and periodate cleavage of the resulting glycol (5) affords daunomycinone‐14‐^14^C (6). Bromination and hydrolysis of 6 gives adriamycinone‐14‐^14^C (8). Coupling of 6 and the 14‐0‐p‐anisyldiphenyl‐methyl derivative (9) with 1‐chloro‐3‐N