Interaction of the σ2 Receptor Ligand PB28 with the Human Nucleosome: Computational and Experimental Probes of Interaction with the H2A/H2B Dimer
✍ Scribed by Carmen Abate; Justin Elenewski; Mauro Niso; Francesco Berardi; Nicola Antonio Colabufo; Amalia Azzariti; Roberto Perrone; Richard A. Glennon
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 612 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1860-7179
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📜 SIMILAR VOLUMES
The biologically relevant conformation of substance P is likely to be dictated by the lipid milieu wherein the hormone would interact with its receptor. Assuming that specific constraints to the hormone structure may be imparted by its interaction with Ca 2 + ions in the low dielectric lipid medium,
The yellow-orange boratabenzene complex Cb\*Co(3,5-Me 2 C 5 H 3 BNMe 2 ) (1) (Cb\* = C 4 Me 4 ) was readily obtained from [Cb\*Co(NCMe) 3 ]PF 6 and Li(TMEDA)(3,5-Me 2 C 5 H 3 BNMe 2 ). Methanolysis of 1 afforded Cb\*Co(3,5-Me 2 C 5 H 3 BOMe) (2). Complex 2 reacted with MeLi and with BCl 3 to give th