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Interaction of the human plasma membrane monoamine transporter (hPMAT) with antidepressants and antipsychotics

✍ Scribed by Britta Haenisch; Heinz Bönisch

Book ID
105876974
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
195 KB
Volume
381
Category
Article
ISSN
0028-1298

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Interaction of the human plasma membrane
Interaction of the human plasma membrane monoamine transporter (hPMAT) with antidepressants and antipsychotics
✍ Britta Haenisch; Heinz Bönisch 📂 Article 📅 2009 🏛 Springer-Verlag 🌐 English ⚖ 195 KB

Monoamine neurotransmission is efficiently terminated through synaptic reuptake of released neurotransmitters by high-affinity Na(+)- and Cl(-)-dependent neuronal monoamine transporters of the SLC6A family located in the plasma membrane of presynaptic nerve terminals. Recently, a low-affinity, high-