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Interaction of the C-Terminal Region of the Gγ Protein with Model Membranes

✍ Scribed by Barceló, Francisca; Prades, Jesús; Encinar, José Antonio; Funari, Sérgio S.; Vögler, Oliver; González-Ros, José Manuel; Escribá, Pablo V.


Book ID
119920952
Publisher
Biophysical Society
Year
2007
Tongue
English
Weight
420 KB
Volume
93
Category
Article
ISSN
0006-3495

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The C-terminal domain of the heterotrimeric G protein a-subunits plays a key role in selective activation of G proteins by their cognate receptors. Several C-terminal fragments of Galpha(s) (from 11 to 21 residues) were recently synthesized. The ability of these peptides to stimulate agonist binding