✦ LIBER ✦
Interaction of the alkylating agent mechlorethamine with DNA in presence and in absence of the radioprotector WR-1065: A transient electric birefringence study
✍ Scribed by Georges Mallet; Jean Lematre; Dan Vasilescu
- Publisher
- Springer Netherlands
- Year
- 1996
- Tongue
- English
- Weight
- 778 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0092-0606
No coin nor oath required. For personal study only.
✦ Synopsis
A transient electric birefringence computerized spectrometer inducing Kerr effect in anisotropically polarizable solutions as DNA has been used to investigate, at ambient temperature, the mechlorethamine-DNA interaction in presence and in absence of the WR-1065 radioprotector. The birefringence, and the time relaxation variations versus drug concentration are reported. An interpretation including DNA electrooptic properties is proposed.