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Interaction of tau protein with the dynactin complex

โœ Scribed by Magnani, Enrico; Fan, Juan; Gasparini, Laura; Golding, Matthew; Williams, Meredith; Schiavo, Giampietro; Goedert, Michel; Amos, Linda A; Spillantini, Maria Grazia


Book ID
110032250
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
358 KB
Volume
26
Category
Article
ISSN
0261-4189

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## Abstract Impaired axonal transport may promote pathogenesis in neurodegenerative disorders, such as Alzheimer's disease (AD). We previously showed that tau, amyloid precursor protein (APP), and intracellular amyloid ฮฒโ€protein (Aฮฒ) accumulate in the nerveโ€ending fraction of aged monkey brains, pe