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Interaction of specific neurotoxins with voltage-sensitive Na-channels in membrane vesicles

✍ Scribed by H. H. Grünhagen


Publisher
Springer
Year
1981
Tongue
English
Weight
119 KB
Volume
7
Category
Article
ISSN
1432-1017

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Interaction of polypeptide neurotoxins w
✍ Catterall, William A. ;Beneski, Daniel A. 📂 Article 📅 1980 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 550 KB

## Abstract Anthopleurin A, a polypeptide toxin from the Pacific sea anemone Anthopleura xanthogrammica, enhances persistent activation of voltage‐senstive sodium channels by the alkaloid toxins veratridine and batrachotoxin with K~0.5~ = 20 nM. This effect is inhibited by depolarization. There is