Interaction of remote functional groups (amide and amine) in steroidal compounds after electron ionization
✍ Scribed by Pierre Longevialle; Guy Bouchoux; Yannik Hoppilliard
- Book ID
- 102965843
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 629 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1076-5174
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✦ Synopsis
Electron impact ionization of steroidal compounds with two differently substituted functional groups (amide and amine) at remote positions leads to the interaction of these groups in ion-neutral complexes after the detachment of one of them. Two situations may be encountered, depending on which group is more easily detached from low-energy parent ions: (i) when the formation of the immonium ion is preferred, a very efficient proton transfer to the amide is observed leading to abundant [ Mimine]" and subsequent daughter ions; (ii) when the detachment of the amide is preferred, hydrogen exchanges occur with the amine group, and fragment ions may be observed resulting from the addition of both groups in a proton-bound structure.