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Interaction of poly(rC)-binding protein 2 with the 5′-terminal stem loop of the hepatitis C-virus genome

✍ Scribed by Shuetsu Fukushi; Masato Okada; Tsutomu Kageyama; Fuminori B Hoshino; Katsuya Nagai; Kazuhiko Katayama


Book ID
117365615
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
398 KB
Volume
73
Category
Article
ISSN
0168-1702

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Interferons (IFNs) and the interferon-stimulated genes (ISGs) play a central role in antiviral responses against hepatitis C virus (HCV) infection. We have reported previously that ISGs, including guanylate binding protein 1 (GBP-1), interferon alpha inducible protein (IFI)-6-16, and IFI-27, inhibit