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Interaction of nitric oxide and serotonin in aggressive behavior

✍ Scribed by Silvana Chiavegatto; Randy J Nelson

Book ID
116982063
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
145 KB
Volume
44
Category
Article
ISSN
0018-506X

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Male mice with targeted deletion of the genes encoding the neuronal (NOS -1K/K or nNOS K/K ) isoform of nitric oxide synthase display altered aggressive behaviors. Male nNOS -1K/K mice are more aggressive than wild-type (WT) mice in all testing paradigms. Testosterone is necessary, but not sufficien