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Interaction of natriuretic peptides and cGMP production via the same receptor in mouse astrocytes

โœ Scribed by C.W.K. Ngai; S.L.N. Ng; C.S. Cockram; C.M. Lee; V.T.F. Yeung; M.G. Nicholls

Book ID
115803254
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
427 KB
Volume
589
Category
Article
ISSN
0006-8993

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## Abstract Cardiac remodeling involves the accumulation of extracellular matrix (ECM) proteins including fibronectin (FN). FN contains RGD motifs that bind integrins at DDX sequences allowing signaling from the ECM to the nucleus. We noted that the natriuretic peptide receptor A (NPRโ€A) sequence c