## Abstract In culture, B16/C3 murine melanoma cells grown in the presence of serum undergo melanogenesis at a specific time after plating. At this time, melanin is synthesized intracellularly and then secreted into the extracellular culture fluid. We have found that melanin secretion is dependent
Interaction of methotrexate with melanins and melanosomes from B16 melanoma
✍ Scribed by T. Wilczok; K. Stȩpień; E. Buszman; M. Porȩbska-Budny
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 472 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0301-4622
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Stable heat‐resistant clones were selected from wild‐type B‐16 melanoma cells and from three of their surface variants resistant to the lectins wheat‐germ agglutinin, ricin and concanavalin A. The selection procedure included three or four cycles of heating the cells in culture at 43°C
Background and Objectives: Dendritic cells (DC) pulsed in vitro with a variety of antigens have proved effective in producing specific antitumor effects in vivo. Experimental evidence from other laboratories has confirmed that shared antigens can be encountered in histologically distinct tumors. In