Interaction of liposomes with proteins measured by surface plasmon resonance correlates with their in vivo circulation time

Unbinding forces of single pertussis tox

Unbinding forces of single pertussis toxin–antibody complexes measured by atomic force spectroscopy correlate with their dissociation rates determined by surface plasmon resonance

✍ Nadège Moreno; Michel Chevalier; Frédéric Ronzon; Catherine Manin; Monique Dupuy 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 572 KB

An inactivated form of pertussis toxin (PTX) is the primary component of currently available acellular vaccines against __Bordetella pertussis__, the causative agent of whooping cough. The PTX analyzed here is purified at industrial scale and is subsequently inactivated using glutaraldehyde. The inf