Interaction of lac repressor with alternating poly d (A-T) and poly d (G-C). Circular dichroism studies
โ Scribed by Durand, Maurice; Maurizot, Jean-Claude
- Book ID
- 122927294
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 368 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0300-9084
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The binding of polyamines, including spermidine ( 1 ) and spermine ( 2 ) , to poly [ d (G-C) \* d( G-C) ] was probed using spectroscopic studies of anthracene-9-carbonyl-N'-spermine (3 ) ; data from normal absorption, linear dichroism (LD ) , and circular dichroism (CD) are reported. Ligand LD and C
Model helices for poly[d(A)]-poly[d(T)] in solution were constructed based on the base orientations determined by linear dichroisxn [LD; S. P. Edmondson & W. C. Johnson, Jr. (1985) Bwpolymers 24,824-8411 and refined by molecular mechanical energy minimization. The results demonstrate that poly[d(A)]